How Fasting Affects the Brain
- caerohealthcare
- Feb 20
- 1 min read
Updated: Mar 18

A new study reveals that fasting triggers significant changes in brain regions linked to appetite regulation and addiction. At the same time, stool and blood sample analyses showed notable shifts in gut bacteria, particularly in the presence of Coprococcus comes and Eubacterium hallii. Published in Frontiers in Cellular and Infection Microbiology, the research highlights the deep connection between fasting, gut microbiota, and brain function.
Participants in the study not only lost an average of 7.6 kilograms (16.8 pounds) but also experienced measurable changes in their gut bacteria composition and brain activity. One key finding was reduced activity in the left inferior frontal orbital gyrus, a brain region involved in controlling food intake. This suggests that intermittent fasting may promote the growth of beneficial gut bacteria that produce compounds influencing brain function, particularly in areas linked to appetite and impulse control.
These findings reinforce the concept of a dynamic gut-brain connection, where changes in gut bacteria can directly impact brain activity, potentially shaping eating behaviors and decision-making related to food. Beyond weight loss, intermittent fasting has been associated with improved metabolic health, enhanced cognitive function, and even potential longevity benefits, making it a powerful tool for overall well-being.
Comments